{"title":"Store Category","description":"","products":[{"product_id":"ossialabs-osstivia","title":"Osstivia SNEDDS","description":"\u003cp\u003e\u003cmeta charset=\"utf-8\"\u003e \u003cmeta name=\"viewport\" content=\"width=device-width,initial-scale=1,viewport-fit=cover\"\u003e \u003cmeta name=\"color-scheme\" content=\"light\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003clink rel=\"preconnect\" href=\"https:\/\/unpkg.com\" crossorigin=\"\"\u003e \u003clink rel=\"preconnect\" href=\"https:\/\/cdn.jsdelivr.net\" crossorigin=\"\"\u003e \u003cscript src=\"https:\/\/unpkg.com\/lucide@latest\"\u003e\u003c\/script\u003e\u003c\/p\u003e\n\u003cstyle\u003e\n    \/* ============================== *\/\n    \/* OSSIALABS LIGHT THEME      *\/\n    \/* ============================== *\/\n    #ossialabs-product{\n      --bg:#f7f8fc; --paper:#ffffff; --ink:#0f172a; --mut:#475569;\n      --brand:#dc2626;\n      --ring:rgba(220, 38, 38, 0.18);\n      --ok:#dc2626; --soft:#f1f5f9; --r:14px;\n      --shadow:0 12px 30px rgba(2,6,23,.10), 0 2px 8px rgba(2,6,23,.06);\n      --shadow-strong:0 14px 38px rgba(2,6,23,.18), 0 4px 16px rgba(2,6,23,.10);\n      --fx1:40% 20%; --fx2:80% 60%; --fx3:15% 85%;\n      color:var(--ink); background:var(--bg);\n      font:16px\/1.6 system-ui,-apple-system,Segoe UI,Roboto,Arial,sans-serif;\n      position:relative; overflow:clip; -webkit-font-smoothing:antialiased; text-rendering:optimizeLegibility;\n    }\n    .wrap{max-width:920px;margin:0 auto;padding:clamp(12px,3vw,24px)}\n    h1{margin:0 0 6px;font-weight:900;letter-spacing:-.02em;font-size:clamp(1.9rem,5vw,3rem)}\n    h2{margin:1.4rem 0 .6rem;font-weight:900;font-size:clamp(1.1rem,3vw,1.5rem); letter-spacing: -.01em;}\n    h3{margin:1rem 0 .4rem;font-weight:800;font-size:1rem; color: var(--ink);}\n    p.lead{color:var(--mut);margin:.25rem 0 1rem; font-size: 1.05rem;}\n    p{margin-bottom: 1rem; color: var(--ink);}\n    a{color:var(--brand);text-decoration:none}\n    a:hover{text-decoration:underline}\n\n    .card{background:var(--paper);border:1px solid var(--ring);border-radius:var(--r);padding:24px;margin-top:1rem;box-shadow:var(--shadow)}\n\n    \/* Pills \u0026 buttons *\/\n    .pill{display:inline-flex;align-items:center;gap:8px;border-radius:999px;padding:.5rem .8rem;font-weight:700;font-size:.9rem;border:1px solid var(--ring);background:var(--soft);color:var(--ink);cursor:pointer;text-decoration:none; margin-right: 6px; margin-bottom: 6px;}\n    .pill.brand{background:var(--brand);color:#fff;border-color:rgba(0,0,0,.05);box-shadow:0 4px 10px rgba(0,0,0,.12)}\n    .pill .icon{width:16px;height:16px}\n\n    \/* Feature list *\/\n    .feature-list{list-style:none;padding:0;margin:.5rem 0 0}\n    .feature-list li{display:flex;gap:12px;align-items:flex-start;margin:.85rem 0}\n    .feature-list i{width:22px;height:22px;color:var(--ok); flex-shrink: 0; margin-top: 3px;}\n\n    \/* Data Table *\/\n    .dose-table { width: 100%; border-collapse: collapse; margin-top: 10px; font-size: 0.9rem; }\n    .dose-table th { text-align: left; border-bottom: 2px solid var(--soft); padding: 8px; color: var(--mut); font-weight: 700; }\n    .dose-table td { border-bottom: 1px solid var(--soft); padding: 8px; color: var(--ink); }\n    .dose-table tr:last-child td { border-bottom: none; }\n\n    \/* Background effects *\/\n    .fx-bg{position:absolute; inset:-20vmax -10vmax -20vmax -10vmax; pointer-events:none; z-index:0;\n      background:\n        radial-gradient(40vmax 40vmax at var(--fx1), rgba(220, 38, 38, 0.15), transparent 70%),\n        radial-gradient(34vmax 34vmax at var(--fx2), rgba(239, 68, 68, 0.14), transparent 70%),\n        radial-gradient(30vmax 30vmax at var(--fx3), rgba(185, 28, 28, 0.10), transparent 70%);\n      filter:saturate(110%) blur(0.5px);\n      transform: translate3d(0, calc(var(--scrollY,0) * -0.12px), 0);\n      transition:opacity .5s ease;\n    }\n    .content{position:relative; z-index:1}\n\n    \/* Reveal *\/\n    .reveal{opacity:0;transform:translateY(8px);transition:opacity .6s ease,transform .6s ease}\n    .in{opacity:1;transform:none}\n\n    \/* Print *\/\n    @media print{\n      #ossialabs-product{ color:#000; background:#fff }\n      .card{ box-shadow:none; border:1px solid #ddd; break-inside:avoid }\n      .reveal{ opacity:1; transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"ossialabs-product\" lang=\"en\" role=\"region\" aria-label=\"Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eOsstivia SNEDDS: Bone Modulation\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eAn experimental, high-bioavailability evolution of \u003cem\u003eFructus Ligustri Lucidi\u003c\/em\u003e Extract. Osstivia utilizes a Self nano-emulsifying dietary delivery system (SNEDDS) to increase the bioavailability and permeation of lipophilic botanical compounds shown to actively promote bone growth, remodeling, increase bone density, increase osteoblast activity, and inhibit osteoclasts.\u003c\/p\u003e\n\n\u003cdiv style=\"background: var(--soft); border-radius: 8px; padding: 14px; margin-top: 16px; margin-bottom: 16px; border: 1px solid var(--ring);\"\u003e\n\u003cdiv style=\"display: flex; gap: 8px; align-items: center; font-weight: 800; color: var(--brand); font-size: 1.05rem;\"\u003e\n\u003ci data-lucide=\"zap\" style=\"width: 20px; height: 20px;\"\u003e\u003c\/i\u003e April 2026 Formula Update\n\u003c\/div\u003e\n\u003cp style=\"margin-top: 6px; margin-bottom: 0; font-size: 0.95rem; color: var(--ink);\"\u003e\n\u003cem\u003eDaemonorops Draco\u003c\/em\u003e has been completely removed to make room for \u003cstrong\u003e3X more Fructus Ligustri Lucidi (FLL)\u003c\/strong\u003e compared to previous batches. Customers should expect even better performance and targeted results.\n\u003c\/p\u003e\n\u003c\/div\u003e\n\n\u003cp class=\"lead\"\u003eBeyond bone modulation, Osstivia also acts as a natural anabolic for muscle support and a great health supplement. Osstivia by itself won't magically grow bone, it is only there to increase the rate of your results and boost them. In simple words, Osstivia is a booster that helps with existing stimulation. You need to pair it with a mechanical load that stimulates growth, like chewing hard gum that is enough for strain.\u003c\/p\u003e\n\n\u003cdiv style=\"margin-top: 12px;\"\u003e\n\u003ca class=\"pill brand\" href=\"#protocol\"\u003e\u003ci class=\"icon\" data-lucide=\"biceps-flexed\"\u003e\u003c\/i\u003e Chew Protocol\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"#care\"\u003e\u003ci class=\"icon\" data-lucide=\"alert-circle\"\u003e\u003c\/i\u003e Care \u0026amp; Usage\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"tech-h\"\u003e\n\u003ch2 id=\"tech-h\"\u003eThe SNEDDS Advantage\u003c\/h2\u003e\n\u003cp\u003eAverage supplements cannot bypass first-pass metabolism and end up destroyed during digestion. We are actively advancing the science with what we have, unlike the standard supplement industry.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"zap\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStraight to the Bloodstream.\u003c\/strong\u003e Ossialabs uses a Self nano-emulsifying dietary delivery system (SNEDDS) that literally increases the bioavailability and permeability of active botanical compounds. This helps bypass first-pass metabolism and leads to a good amount of the botanical compounds going straight to the bloodstream.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"target\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSuperior to Powders.\u003c\/strong\u003e Rat studies are mainly used to choose a botanical. While we know rats aren't similar in gut and human digestion, active botanical compounds CAN modulate pathways. By pushing SNEDDS predominantly to close that bioavailability gap, we can achieve more accurate results than just taking \"powder\".\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"flask-conical\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eWe Are The Human Studies.\u003c\/strong\u003e Osstivia SNEDDS is strictly experimental, and our community serves as the early human studies. It shows great promise for the people who have used it, and we plan on conducting formal studies in the future.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"science\" aria-labelledby=\"mech-h\"\u003e\n\u003ch2 id=\"mech-h\"\u003eGrowth Mechanisms \u0026amp; Science\u003c\/h2\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--mut); margin-bottom: 0.5rem;\"\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Osstivia is both \u003cstrong\u003edose and time dependent\u003c\/strong\u003e. Consistent application is required to trigger the growth pathways.\u003c\/p\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--ink); margin-bottom: 1rem; font-weight: 700;\"\u003eBased on data. To include preclinical and emerging clinical data:\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"users\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eClinical Human Trials.\u003c\/strong\u003e A clinical trial involving women taking FLL powder documented significant improvements in bone mineral density. While this study utilized a basic milk powder delivery, it demonstrates massive potential. By utilizing SNEDDS to bypass first-pass metabolism and send compounds straight to the bloodstream, we are engineered to achieve even greater results.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"dna\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTargeted Pathways.\u003c\/strong\u003e Osstivia acts directly on critical bone modulation pathways. Deep pharmacological research shows FLL strongly influences the RANKL-RANK\/TRAF6-NF-kB\/MAPK-NFATc1 axis, suppressing marrow adipogenesis and increasing ALP for mineralization. It also engages the PI3K\/Akt-RUNX2\/OPN and MMP-mediated ECM turnover networks.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"flask-conical\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eCanonical Wnt \u0026amp; BMP-2 Modulation.\u003c\/strong\u003e The enhanced, 3X concentrated \u003cem\u003eFructus Ligustri Lucidi\u003c\/em\u003e in the formulation modulates canonical \u003cstrong\u003eWnt\/β-catenin\u003c\/strong\u003e and BMP-2\/Smad pathways, promoting osteoblastogenesis while decreasing osteoclast drive, Nox4\/ROS, and oxidative stress.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"bone\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eCalcium Optimization.\u003c\/strong\u003e Studies show FLL improves calcium retention, absorption, and deposition by upregulating the PTH\/VDR\/TRPV6 axis, creating a superior mineralization environment.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"biceps-flexed\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eNatural Anabolic Muscle Support.\u003c\/strong\u003e Osstivia contains compounds native to FLL like Ursolic Acid, Oleanolic Acid, and Salidroside. These botanical components function as a natural anabolic, providing promising evidence for supporting muscle health and function. While their role in muscle is well-supported, structural bone changes from these specific isolates are not yet heavily documented in humans.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"protocol\" aria-labelledby=\"syn-h\"\u003e\n\u003ch2 id=\"syn-h\"\u003eMandatory Synergy Protocol for Facial Aesthetics\u003c\/h2\u003e\n\u003cp\u003eOsstivia provides the boost, but mechanical loading provides the results. For facial aesthetics and \u003cstrong\u003econdyle growth \u0026amp; remodeling\u003c\/strong\u003e, hard chewing is mandatory.\u003c\/p\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--ink); font-weight: 600; font-style: italic; border-left: 3px solid var(--brand); padding-left: 10px; margin-bottom: 15px;\"\u003e\"If I can demonstrate that chewing alone could change mandible morphology, even if slightly, would you concede that having a supplement that promotes osteoblast activity would improve chewing alone?\"\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"timer\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003e30 Minute Limit.\u003c\/strong\u003e Chew for a total of \u003cstrong\u003e30 minutes a day\u003c\/strong\u003e. Do NOT chew for hours or constantly clench, as this leads to TMJD and has negative effects on the condyle.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"skull\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eCheekbone \u0026amp; Mandible.\u003c\/strong\u003e Hard chewing grows and remodels the condyle, which leads to improvements in the mandible. That is the growth site of the mandible, that's where growth and rotation happens, and its growth affects chin projection. You MAY potentially get zygo improvements since the zygomatic bones are strained when chewing, which can lead to morphological changes. The reason it might change is because chewing provides dynamic oscillative strain to surrounding sutures. Osstivia is there to increase the rate of chewing results and boost chewing results, so pairing Osstivia with chewing is needed for better results. So, hard chewing with Osstivia will help with chin projection because you are growing the condyle.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"hourglass\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eGrowth Potential.\u003c\/strong\u003e Hypertrophic growth cartilage and condyle remodeling exists even after puberty in the mandible, so keeping bone health up definitely helps take advantage of that. If it increases proliferation, which Osstivia does, it would be enough to boost chewing results. You're not done remodeling the condyle even after your 60s. However, growth is most potent now, so take advantage of being young and hard chew.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"clock\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTiming.\u003c\/strong\u003e Take Osstivia \u003cstrong\u003e10–20 minutes BEFORE\u003c\/strong\u003e your hard chewing session for maximum uptake.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"trending-up\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eRealistic Timelines.\u003c\/strong\u003e You can see decent, minor motivating results in a month or two, but really good results take months (4-6+), or even years. It all depends entirely on how consistent you are with your chewing regimen.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"chew-guide\" aria-labelledby=\"chew-h\"\u003e\n\u003ch2 id=\"chew-h\"\u003eHow to Chew Correctly (Hard Gum)\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"check-square\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eForm \u0026amp; Focus.\u003c\/strong\u003e Open mouth while chewing. Don’t be distracted; focus on the movement.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"refresh-cw\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTechnique.\u003c\/strong\u003e Chew bilaterally (both sides). Position the gum, bite a couple of times, roll the gum with your tongue, and repeat.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"pause-circle\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePacing \u0026amp; Rest.\u003c\/strong\u003e Take rests in between. For example, chew for 1 minute, then rest for 45s–1 min. Rinse and repeat until you hit 30 minutes. \u003cstrong\u003eDo NOT chew for more than 30 minutes total\u003c\/strong\u003e (including rest time).\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"droplet\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eKeep it Tough.\u003c\/strong\u003e If the gum gets soft, use ice water and let it sit in your mouth for a couple of seconds, then resume chewing.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"alert-triangle\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSafety Note.\u003c\/strong\u003e If you have an overbite, contact the Craniofacial Research Collective (CRC) first before chewing.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"care\" aria-labelledby=\"care-h\"\u003e\n\u003ch2 id=\"care-h\"\u003eCare, Usage \u0026amp; Taste Profile\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"pipette\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eHow to Take It.\u003c\/strong\u003e You take Osstivia orally via the dropper that comes with the bottle. The glass dropper is marked with precise measurements so you can easily track your daily mL dosage.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"ban\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eDo NOT:\u003c\/strong\u003e Do not refrigerate. Do not place near the sun. Do not put in super warm liquids. Do NOT shake if the product is already diluted.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"check-circle\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eYou CAN:\u003c\/strong\u003e Take Osstivia by itself or put it in water to drink. You can drink other beverages before or after taking it. You can shake the bottle before use (undiluted). Feel free to pair Osstivia with Vitamin D3, K2, and Calcium to help with it even more, since studies show FLL improves calcium retention and deposition.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"shield-check\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSafety \u0026amp; Toxicology.\u003c\/strong\u003e Osstivia has had no negative side effects reported at all. The botanical compound is well tolerated even in high amounts (though please follow the dosing guide and do not overdose). We encourage you to look into \u003cem\u003eFructus Ligustri Lucidi\u003c\/em\u003e toxicology, as extensive studies show it is remarkably safe and lacks systemic toxicity.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"info\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTaste Profile.\u003c\/strong\u003e This is an advanced formulated product; it does not taste sugary or fake. Some users are sensitive to the excipients, while others don't mind. It is an acquired taste you will get used to.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"dosing\" aria-labelledby=\"dose-h\"\u003e\n\u003ch2 id=\"dose-h\"\u003eNew Measurement Dosing System\u003c\/h2\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--mut);\"\u003eWe have upgraded from drops to a precise measurement dropper (mL). \u003cstrong\u003eStart Low:\u003c\/strong\u003e We recommend starting at 0.5 mL and building up to the optimal dose of 1.0 to 2.0 mL daily.\u003c\/p\u003e\n\n\u003cp style=\"font-size: 0.95rem; color: var(--mut); margin-top: 10px;\"\u003e\u003cstrong\u003eConsistency is Key:\u003c\/strong\u003e Because Osstivia is dose and time-dependent, we highly recommend purchasing a pack of 5-6 bottles (60mL) to maintain a consistent 1-2mL daily protocol alongside your hard chewing. \u003cem\u003e(Note: If you have the budget, 2mL is optimal. Some users have recently started testing 3-6mL daily as well).\u003c\/em\u003e\u003c\/p\u003e\n\n\u003cdiv style=\"background: var(--soft); border-radius: 8px; padding: 12px; margin-top: 16px; margin-bottom: 16px;\"\u003e\n\u003cdiv style=\"display: flex; gap: 10px; align-items: center; font-weight: 700; color: var(--ink);\"\u003e\n\u003ci data-lucide=\"refresh-cw\" style=\"width: 18px;\"\u003e\u003c\/i\u003e Cycle Recommendation\n\u003c\/div\u003e\n\u003cdiv style=\"margin-top: 4px; font-size: 0.9rem; color: var(--mut);\"\u003e\nCycle 3 weeks ON, 1 week OFF.\n\u003c\/div\u003e\n\u003c\/div\u003e\n\n\u003ch3\u003eHow long will your bottle last?\u003c\/h3\u003e\n\u003ctable class=\"dose-table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eDaily Dose\u003c\/th\u003e\n\u003cth\u003e30mL Bottle\u003c\/th\u003e\n\u003cth\u003e60mL Bottle\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e0.5 mL\u003c\/strong\u003e (Low)\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003ctd\u003e4 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.0 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.5 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 Days\u003c\/td\u003e\n\u003ctd\u003e40 Days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e2.0 mL\u003c\/strong\u003e (Max)\u003c\/td\u003e\n\u003ctd\u003e2 Weeks\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"ref-h\"\u003e\n\u003ch2 id=\"ref-h\"\u003eScientific References\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px; font-size: 0.85rem; color: var(--mut);\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eChen et al. Fructus Ligustri Lucidi in Osteoporosis: A Review of its Pharmacology, Phytochemistry, Pharmacokinetics and Safety. Molecules. 2017;22:1469.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eXu et al. Fructus Ligustri Lucidi ethanol extract inhibits osteoclastogenesis in RAW264.7 cells via the RANKL signaling pathway. Molecular Medicine Reports. 2016;14:4767-4774.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eKong et al. The potential mechanism of Fructus Ligustri Lucidi promoting osteogenetic differentiation of BMSCs based on network pharmacology, molecular docking and experimental identification. Bioengineered. 2022;13:10640-10653.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eChen, B., Wei, J., Zhu, R., et al. (2021). Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats. Journal of Ethnopharmacology, 279, 114348.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eTang XF, Ma ZT, Gao YY, et al. Systemic osteoprotective effects of Epimedii Folium and Ligustri Lucidi Fructus in senile osteoporosis rats by promoting the osteoblastogenesis and osteoclastogenesis based on MLP-ANN model. Chin Med. 2020;15:87.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eLi L, Chen B, Zhu R, et al. Fructus Ligustri Lucidi preserves bone quality through the regulation of gut microbiota diversity, oxidative stress, TMAO and Sirt6 levels in aging mice. Aging (Albany NY). 2019;11(21):9348-9368.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eChen L, Huang D, Jiang L, et al. A review of botany, phytochemistry, pharmacology, and applications of the herb with the homology of medicine and food: Ligustrum lucidum W.T. Aiton. Front. Pharmacol. 2024;15:1330732.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eA Milk Product Supplemented with a Herbal Extract for the Prevention of Osteoporosis: Justifications and Clinical Trial. Leung et al. Journal of Food and Nutrition Sciences. (2015).\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eKapoor et al. Biomolecular signals in mandibular condylar cartilage: Bioinformatics and evidence-based insights for optimizing functional appliance therapy. Seminars in Orthodontics. 2025.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eYang and Ren. Factors Involved in Mandibular Condylar Growth: An Overview. Oral Health and Dental Management. 2014;13:1019-1023.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eYang et al. Mechanoresponsive and lubricating changes of mandibular condylar cartilage associated with mandibular lateral shift and recovery in the growing rat. Clinical Oral Investigations. 2020;24:3547-3557.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eFLL osteoporosis studies summarized in FLL pharmacology and bone-quality literature, including canonical Wnt\/beta-catenin signaling.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eOsteoblast-osteoclast communication and OPG\/RANKL\/cathepsin K pathways reported in FLL bone-remodeling studies.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003ePTHrP\/Ihh\/Sox9 condylar growth axis described in mandibular condylar cartilage growth and MCC development literature.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eLigustri Lucidi Fructus postmenopausal osteoporosis studies identifying BMP-Smad\/Runx2-related mechanisms.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eFLL bone studies reporting Nrf2\/HO-1 and ferroptosis-related osteoporosis mechanisms.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.85rem; text-align: center;\"\u003e© Ossialabs — Advanced research-backed formulations.\u003cbr\u003eStatements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n    \/* Reveal animation *\/\n    (function(){\n      try{\n        const io=new IntersectionObserver(es=\u003e{ es.forEach(e=\u003e{ if(e.isIntersecting){ e.target.classList.add('in'); io.unobserve(e.target);} }); },{threshold:.12});\n        document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eio.observe(el));\n      }catch(e){ document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eel.classList.add('in')); }\n    })();\n\n    \/* Parallax background *\/\n    (function(){\n      const root=document.getElementById('ossialabs-product');\n      let ticking=false, lastY=0;\n      function onScroll(){ lastY = window.scrollY || document.documentElement.scrollTop || 0; if(!ticking){ requestAnimationFrame(()=\u003e{ root.style.setProperty('--scrollY', String(lastY)); ticking=false;}); ticking=true; } }\n      window.addEventListener('scroll', onScroll, {passive:true}); 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font-size: 1.05rem;}\n    p{margin-bottom: 1rem; color: var(--ink);}\n    a{color:var(--brand);text-decoration:none}\n    a:hover{text-decoration:underline}\n\n    .card{background:var(--paper);border:1px solid var(--ring);border-radius:var(--r);padding:24px;margin-top:1rem;box-shadow:var(--shadow)}\n\n    \/* Pills \u0026 buttons *\/\n    .pill{display:inline-flex;align-items:center;gap:8px;border-radius:999px;padding:.5rem .8rem;font-weight:700;font-size:.9rem;border:1px solid var(--ring);background:var(--soft);color:var(--ink);cursor:pointer;text-decoration:none; margin-right: 6px; margin-bottom: 6px;}\n    .pill.brand{background:var(--brand);color:#fff;border-color:rgba(0,0,0,.05);box-shadow:0 4px 10px rgba(0,0,0,.12)}\n    .pill .icon{width:16px;height:16px}\n\n    \/* Feature list *\/\n    .feature-list{list-style:none;padding:0;margin:.5rem 0 0}\n    .feature-list li{display:flex;gap:12px;align-items:flex-start;margin:.85rem 0}\n    .feature-list i{width:22px;height:22px;color:var(--ok); flex-shrink: 0; margin-top: 3px;}\n\n    \/* Data Table *\/\n    .dose-table { width: 100%; border-collapse: collapse; margin-top: 10px; font-size: 0.9rem; }\n    .dose-table th { text-align: left; border-bottom: 2px solid var(--soft); padding: 8px; color: var(--mut); font-weight: 700; }\n    .dose-table td { border-bottom: 1px solid var(--soft); padding: 8px; color: var(--ink); }\n    .dose-table tr:last-child td { border-bottom: none; }\n\n    \/* Background effects *\/\n    .fx-bg{position:absolute; inset:-20vmax -10vmax -20vmax -10vmax; pointer-events:none; z-index:0;\n      background:\n        radial-gradient(40vmax 40vmax at var(--fx1), rgba(5, 150, 105, 0.15), transparent 70%),\n        radial-gradient(34vmax 34vmax at var(--fx2), rgba(16, 185, 129, 0.14), transparent 70%),\n        radial-gradient(30vmax 30vmax at var(--fx3), rgba(52, 211, 153, 0.10), transparent 70%);\n      filter:saturate(110%) blur(0.5px);\n      transform: translate3d(0, calc(var(--scrollY,0) * -0.12px), 0);\n      transition:opacity .5s ease;\n    }\n    .content{position:relative; z-index:1}\n\n    \/* Reveal *\/\n    .reveal{opacity:0;transform:translateY(8px);transition:opacity .6s ease,transform .6s ease}\n    .in{opacity:1;transform:none}\n\n    \/* Print *\/\n    @media print{\n      #ossialabs-japonicus{ color:#000; background:#fff }\n      .card{ box-shadow:none; border:1px solid #ddd; break-inside:avoid }\n      .reveal{ opacity:1; transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"ossialabs-japonicus\" lang=\"en\" role=\"region\" aria-label=\"Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eHumulus Japonicus SNEDDS\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eAn experimental, high-absorption botanical extract based on the latest \u003cstrong\u003eMay 2025\u003c\/strong\u003e preclinical research. Formulated by Ossialabs to target growth pathways (JAK3\/STAT5\/IGF1), support bone health, and promote systemic health.\u003c\/p\u003e\n\u003cdiv style=\"margin-top: 12px;\"\u003e\n\u003ca class=\"pill brand\" href=\"#height\"\u003e\u003ci class=\"icon\" data-lucide=\"flask-conical\"\u003e\u003c\/i\u003e The Science \u0026amp; Promise\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"#dosing\"\u003e\u003ci class=\"icon\" data-lucide=\"pipette\"\u003e\u003c\/i\u003e Dosing Guide\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"tech-h\"\u003e\n\u003ch2 id=\"tech-h\"\u003eThe SNEDDS Advantage\u003c\/h2\u003e\n\u003cp\u003e\u003cem\u003eHumulus japonicus\u003c\/em\u003e is naturally lipophilic, making it difficult to absorb. Average supplements cannot bypass first-pass metabolism and end up destroyed during digestion. We are actively advancing the science by solving this gap.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"zap\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStraight to the Bloodstream.\u003c\/strong\u003e Ossialabs uses a Self nano-emulsifying dietary delivery system (SNEDDS) that dramatically increases the bioavailability and permeability of active compounds. This helps bypass first-pass metabolism, allowing a significant amount of the botanical compound to go straight into the bloodstream.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"target\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSuperior to Powders.\u003c\/strong\u003e By closing the bioavailability gap, our SNEDDS formulation achieves much more accurate and potent results than taking standard botanical \"powders.\"\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"height\" aria-labelledby=\"height-h\"\u003e\n\u003ch2 id=\"height-h\"\u003eExperimental Research \u0026amp; Support\u003c\/h2\u003e\n\u003cp class=\"lead\" style=\"margin-bottom: 0.5rem;\"\u003eRecent preclinical papers (May 2025 release) have highlighted \u003cem\u003eH. japonicus\u003c\/em\u003e for its significant potential in bone growth promotion.\u003c\/p\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--mut); margin-bottom: 1rem;\"\u003e\u003cstrong\u003eImportant:\u003c\/strong\u003e Japonicus is highly dose-dependent. You need to make sure your growth plates are opened if you are wanting to get some height gains.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"flask-conical\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eWe Are The Human Studies.\u003c\/strong\u003e Rat studies are mainly used to identify promising botanicals. While rat and human digestion differ, botanical compounds \u003cem\u003ecan\u003c\/em\u003e and do modulate biological pathways across species. By using SNEDDS to solve the human digestion gap, we are testing its true potential. This product is strictly experimental. Our community is serving as the early human studies, with formal trials planned for the future, but it has already shown great promise for those who use it.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"microscope\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePreclinical Mechanisms.\u003c\/strong\u003e Findings point towards the modulation of \u003cstrong\u003eIGF-1\u003c\/strong\u003e and \u003cstrong\u003eGrowth Hormone (GH)\u003c\/strong\u003e levels, acting via the \u003cstrong\u003eJAK3\/STAT5\/IGF1\u003c\/strong\u003e pathways to support vertical growth and bone health.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"trending-up\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePreclinical Data \u0026amp; Patents.\u003c\/strong\u003e In controlled studies, high-dose groups demonstrated significant longitudinal bone growth rate increases, with femur and tibia length enhancements comparable to the Growth Hormone (GH) control group. Micro-CT scans also revealed significantly denser trabecular bone microarchitecture. Furthermore, the extract is backed by a recognized U.S. Patent for its composition in promoting height growth.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"ruler\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eWindow of Opportunity.\u003c\/strong\u003e Research suggests maximum efficacy for height increase during puberty and while growth plates are still open.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"care\" aria-labelledby=\"care-h\"\u003e\n\u003ch2 id=\"care-h\"\u003eCare, Usage \u0026amp; Taste Profile\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"ban\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eDo NOT:\u003c\/strong\u003e Do not refrigerate. Do not place near the sun or in super warm liquids. Do NOT shake if the product is already diluted.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"check-circle\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eYou CAN:\u003c\/strong\u003e Take Japonicus by itself or put it in water to drink. You can drink other beverages before or after taking it.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"moon\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBest Time.\u003c\/strong\u003e Many customers prefer to take it \u003cstrong\u003ebefore sleep\u003c\/strong\u003e.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"info\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eTaste Profile.\u003c\/strong\u003e This is an advanced formulated product without sugary fillers. Some users (including the founder) find the excipients strong, while others don't mind it. It is an acquired taste you will get used to.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"benefits\" aria-labelledby=\"health-h\"\u003e\n\u003ch2 id=\"health-h\"\u003eBeyond Bone: Systemic Health\u003c\/h2\u003e\n\u003cp\u003eEven outside of growth modulation, \u003cem\u003eHumulus japonicus\u003c\/em\u003e remains a powerhouse ingredient with a wide range of documented health benefits. Recent studies demonstrate that the extract exhibits powerful antioxidative and anti-aging effects through the modulation of the \u003cstrong\u003eAMPK-SIRT1 pathway\u003c\/strong\u003e.\u003c\/p\u003e\n\u003cdiv style=\"display: grid; grid-template-columns: 1fr 1fr; gap: 10px; margin-top: 15px;\"\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eAnti-Inflammatory\u003c\/div\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eAntioxidant\u003c\/div\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eNeuroprotective\u003c\/div\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eAnti-Aging\u003c\/div\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eBone Promotion\u003c\/div\u003e\n    \u003cdiv class=\"pill\" style=\"justify-content: center; cursor: default;\"\u003eGut Support\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"dosing\" aria-labelledby=\"dose-h\"\u003e\n\u003ch2 id=\"dose-h\"\u003eNew Measurement Dosing System\u003c\/h2\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--mut);\"\u003eWe have upgraded from drops to a precise measurement dropper (mL). \u003cstrong\u003eStart Low:\u003c\/strong\u003e We recommend starting at 0.5 mL and building up to the max of 2.0 mL.\u003c\/p\u003e\n\n\u003ch3\u003eHow long will your bottle last?\u003c\/h3\u003e\n\u003ctable class=\"dose-table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eDaily Dose\u003c\/th\u003e\n\u003cth\u003e30mL Bottle\u003c\/th\u003e\n\u003cth\u003e60mL Bottle\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e0.5 mL\u003c\/strong\u003e (Low)\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003ctd\u003e4 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.0 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.5 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 Days\u003c\/td\u003e\n\u003ctd\u003e40 Days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e2.0 mL\u003c\/strong\u003e (Max)\u003c\/td\u003e\n\u003ctd\u003e2 Weeks\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"font-size: 0.85rem; color: var(--mut); margin-top: 10px;\"\u003e\u003cem\u003eNote: 10 drops is approximately 0.5 mL. Max recommended dose is 2mL\/day.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"ref-h\"\u003e\n\u003ch2 id=\"ref-h\"\u003eKey Research \u0026amp; References\u003c\/h2\u003e\n\u003cp style=\"font-size: 0.9rem; margin-bottom: 0.5rem; color: var(--mut);\"\u003eOur formulation is based on the following recent preclinical studies and patents:\u003c\/p\u003e\n\u003cul style=\"padding-left: 20px; font-size: 0.85rem; color: var(--mut);\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eKim OK, Yun JM, Lee M, Park SJ, Kim D, Oh DH, Kim HS, Kim GY. A Mixture of Humulus japonicus Increases Longitudinal Bone Growth Rate in Sprague Dawley Rats. Nutrients. 2020 Aug 28;12(9):2625.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003ePark SH, Park J, Yoo JY, Kim HS, Lee M, Kim OK. Humulus japonicus Enhances Bone Growth and Microarchitecture in Rats: Potential Involvement of IGF-1 Signaling. J Med Food. 2025 Jun;28(6):542-552.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eKim, O. K., et al. (2023). Food composition for promoting height growth and pharmaceutical composition for promoting height growth including Humulus japonicus extract. U.S. Patent Application No. 18\/456,888. Washington, DC: U.S. Patent and Trademark Office.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eSung B, Chung JW, Bae HR, Choi JS, Kim CM, Kim ND. Humulus japonicus extract exhibits antioxidative and anti-aging effects via modulation of the AMPK-SIRT1 pathway. Exp Ther Med. 2015 May;9(5):1819-1826.\u003c\/em\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.85rem; text-align: center;\"\u003e© Ossialabs — Advanced Research Formulations.\u003cbr\u003eStatements have not been evaluated by the FDA. 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border:1px solid #ddd; break-inside:avoid }\n      .reveal{ opacity:1; transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"crc-donate\" lang=\"en\" role=\"region\" aria-label=\"Ossialabs Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eAdvanced Humulus Lupulus SNEDDS\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eA breakthrough nanoemulsion formulation of Common Hops designed to maximize bioavailability. Specially formulated mainly for women, harnessing the power of xanthohumol for hormone balance, metabolic health, and broad-spectrum support.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003csection class=\"card reveal\" aria-labelledby=\"mech-h\"\u003e\n\u003ch2 id=\"mech-h\"\u003eMechanism of Action \u0026amp; Benefits\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"atom\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSNEDDS Emulsion Technology.\u003c\/strong\u003e By harnessing the power of emulsion formulation, we maximize the bioavailability of xanthohumol and other key compounds that are normally difficult for the body to absorb.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"activity\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eMetabolic \u0026amp; Diabetic Support.\u003c\/strong\u003e Research shows that xanthohumol inhibits α-glucosidase and helps with insulin resistance, effectively aiding in blood sugar management.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"shield-plus\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBroad Research Profile.\u003c\/strong\u003e Emerging research on this herb indicates a wide range of potential effects including: sedative, anxiolytic, antidepressant, sleep-promoting, anti-inflammatory, antioxidant, antimicrobial, anticancer, phytoestrogenic \u0026amp; estrogenic modulation, anti-obesity, anti-angiogenic, anti-biofilm, hepatoprotective, cardioprotective, neuroprotective, gastrointestinal support, and enzyme inhibition (e.g., acetylcholinesterase, α-amylase, urease).\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\u003csection class=\"card reveal\" aria-labelledby=\"note-h\"\u003e\n\u003ch2 id=\"note-h\"\u003eScientist's Note \u0026amp; Case Study\u003c\/h2\u003e\n\u003cp\u003eWe created a therapeutic version using higher concentrations of Humulus lupulus to test its effects on glucose regulation. The results were profound.\u003c\/p\u003e\n\u003cblockquote style=\"border-left: 4px solid var(--brand); padding-left: 1rem; margin: 1.5rem 0; color: var(--mut); font-style: italic;\"\u003e\"I gave it to a relative with diabetes and menopause... She told me she's been waking up with low blood sugar levels, which hasn't happened before. This is game changing... This means that under this emulsion, one may be able to enjoy more sweets or carbs.\"\u003c\/blockquote\u003e\n\u003cp class=\"lead\" style=\"margin-top: .3rem; font-size: 1rem; font-weight: 600; color: var(--ink)\"\u003eIf you or someone you know deals with diabetes, menopause, or osteoporosis, let us know. We can help by making you this special formulation.\u003c\/p\u003e\n\u003c\/section\u003e\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.9rem;\"\u003e© Ossialabs — Advanced herbal formulations based on emerging research. Statements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n    \/* Reveal animation *\/\n    (function(){\n      try{\n        const io=new IntersectionObserver(es=\u003e{ es.forEach(e=\u003e{ if(e.isIntersecting){ e.target.classList.add('in'); io.unobserve(e.target);} }); },{threshold:.12});\n        document.querySelectorAll('#crc-donate .reveal').forEach(el=\u003eio.observe(el));\n      }catch(e){ document.querySelectorAll('#crc-donate .reveal').forEach(el=\u003eel.classList.add('in')); }\n    })();\n\n    \/* Parallax background *\/\n    (function(){\n      const root=document.getElementById('crc-donate');\n      let ticking=false, lastY=0;\n      function onScroll(){ lastY = window.scrollY || document.documentElement.scrollTop || 0; if(!ticking){ requestAnimationFrame(()=\u003e{ root.style.setProperty('--scrollY', String(lastY)); ticking=false;}); ticking=true; } }\n      window.addEventListener('scroll', onScroll, {passive:true}); 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transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"ossialabs-product\" lang=\"en\" role=\"region\" aria-label=\"Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eBakuchiol Nanoemulgel\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eThe future of plant-based anti-aging. A breakthrough formula using advanced nanotechnology to deliver pure Bakuchiol deep into the skin.\u003c\/p\u003e\n\u003cdiv style=\"margin-top: 12px;\"\u003e\n\u003ca class=\"pill brand\" href=\"#science\"\u003e\u003ci class=\"icon\" data-lucide=\"microscope\"\u003e\u003c\/i\u003e Explore The Science\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"science\" aria-labelledby=\"mech-h\"\u003e\n\u003ch2 id=\"mech-h\"\u003eWhy Nano Matters\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"zap\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eNano Delivery System.\u003c\/strong\u003e If a nanoemulgel isn't used, lipophilic compounds like Bakuchiol have a hard time bypassing the stratum corneum on their own. Our technology creates ultra-fine nano drops that are so small the outer skin layers cannot stop them, ensuring deep penetration and maximum absorption.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"flower-2\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eRetinol Alternative.\u003c\/strong\u003e Bakuchiol offers the same powerful results as Retinol, including smoothing fine lines and increasing cell turnover, but with fewer side effects.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"droplet\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eDeep Hydration.\u003c\/strong\u003e The unique emulgel texture combines the moisturizing power of an emulsion with the lightweight and fast-absorbing feel of a gel.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"ben-h\"\u003e\n\u003ch2 id=\"ben-h\"\u003eSkin Benefits\u003c\/h2\u003e\n\u003cp class=\"lead\" style=\"margin-bottom: 0.5rem;\"\u003eEngineered to work better than standard formulations.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"sparkles\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBoosts Collagen.\u003c\/strong\u003e Triggers natural collagen synthesis to improve elasticity and create firmer, plumper skin.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"shield-check\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eGentle Formulation.\u003c\/strong\u003e Delivers powerful anti-aging benefits without the harsh peeling often caused by synthetic retinoids. \u003cem\u003eNote: While generally well-tolerated, no product is entirely free of potential irritation. Individual sensitivities or allergic reactions to the botanical extract or specific excipients can still occur.\u003c\/em\u003e\n\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"note-h\"\u003e\n\u003ch2 id=\"note-h\"\u003eUsage \u0026amp; Ingredients\u003c\/h2\u003e\n\u003cp\u003eApply a small amount to clean skin daily. Perfect for morning or evening routines. We recommend patch-testing on a small area of skin before full application.\u003c\/p\u003e\n\u003cp style=\"color: var(--mut); font-size: 0.9rem; margin-top: 1rem;\"\u003e\n\u003cstrong\u003eInactive Ingredients:\u003c\/strong\u003e Distilled Water, Tween 80, Propylene Glycol, Organic MCT Oil, Span 80, Carbomer, Triethanolamine, Phenoxyethanol.\n\u003c\/p\u003e\n\u003c\/section\u003e\n\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.85rem; text-align: center;\"\u003e© Ossialabs — Advanced research-backed formulations.\u003cbr\u003eStatements have not been evaluated by the FDA. 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font-size: 1.05rem;}\n    p{margin-bottom: 1rem; color: var(--ink);}\n    a{color:var(--brand);text-decoration:none}\n    a:hover{text-decoration:underline}\n\n    .card{background:var(--paper);border:1px solid var(--ring);border-radius:var(--r);padding:24px;margin-top:1rem;box-shadow:var(--shadow)}\n\n    \/* Pills \u0026 buttons *\/\n    .pill{display:inline-flex;align-items:center;gap:8px;border-radius:999px;padding:.5rem .8rem;font-weight:700;font-size:.9rem;border:1px solid var(--ring);background:var(--soft);color:var(--ink);cursor:pointer;text-decoration:none; margin-right: 6px; margin-bottom: 6px;}\n    .pill.brand{background:var(--brand);color:#fff;border-color:rgba(0,0,0,.05);box-shadow:0 4px 10px rgba(0,0,0,.12)}\n    .pill .icon{width:16px;height:16px}\n\n    \/* Feature list *\/\n    .feature-list{list-style:none;padding:0;margin:.5rem 0 0}\n    .feature-list li{display:flex;gap:12px;align-items:flex-start;margin:.85rem 0}\n    .feature-list i{width:22px;height:22px;color:var(--ok); flex-shrink: 0; margin-top: 3px;}\n\n    \/* Data Table *\/\n    .dose-table { width: 100%; border-collapse: collapse; margin-top: 10px; font-size: 0.9rem; }\n    .dose-table th { text-align: left; border-bottom: 2px solid var(--soft); padding: 8px; color: var(--mut); font-weight: 700; }\n    .dose-table td { border-bottom: 1px solid var(--soft); padding: 8px; color: var(--ink); }\n    .dose-table tr:last-child td { border-bottom: none; }\n\n    \/* Background effects *\/\n    .fx-bg{position:absolute; inset:-20vmax -10vmax -20vmax -10vmax; pointer-events:none; z-index:0;\n      background:\n        radial-gradient(40vmax 40vmax at var(--fx1), rgba(37, 99, 235, 0.15), transparent 70%),\n        radial-gradient(34vmax 34vmax at var(--fx2), rgba(59, 130, 246, 0.14), transparent 70%),\n        radial-gradient(30vmax 30vmax at var(--fx3), rgba(96, 165, 250, 0.10), transparent 70%);\n      filter:saturate(110%) blur(0.5px);\n      transform: translate3d(0, calc(var(--scrollY,0) * -0.12px), 0);\n      transition:opacity .5s ease;\n    }\n    .content{position:relative; z-index:1}\n\n    \/* Reveal *\/\n    .reveal{opacity:0;transform:translateY(8px);transition:opacity .6s ease,transform .6s ease}\n    .in{opacity:1;transform:none}\n\n    \/* Print *\/\n    @media print{\n      #ossialabs-product{ color:#000; background:#fff }\n      .card{ box-shadow:none; border:1px solid #ddd; break-inside:avoid }\n      .reveal{ opacity:1; transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"ossialabs-product\" lang=\"en\" role=\"region\" aria-label=\"Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eDioscorea SNEDDS (\u0026gt;40% Diosgenin)\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eA bioavailability-enhanced botanical formulated to support training performance, cognitive function, and exercise readiness. Utilizing advanced lipid delivery, this standardized Dioscorea extract is engineered to increase the absorption of lipophilic compounds like Dioscin and Diosgenin to support muscle quality, brain health, and workout adaptation.\u003c\/p\u003e\n\u003cdiv style=\"margin-top: 12px;\"\u003e\n\u003ca class=\"pill brand\" href=\"#science\"\u003e\u003ci class=\"icon\" data-lucide=\"microscope\"\u003e\u003c\/i\u003e The Science\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"#dosing\"\u003e\u003ci class=\"icon\" data-lucide=\"pipette\"\u003e\u003c\/i\u003e Dosing Guide\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"https:\/\/ossialabs.com\/blogs\/news\/diosgenin-protodioscin-and-diosgenin-snedds-comparative-anabolic-potential-pharmacokinetics-safety-and-implications-for-human-trials\" target=\"_blank\"\u003e\u003ci class=\"icon\" data-lucide=\"book-open\"\u003e\u003c\/i\u003e Read the Deep Dive\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"#coa\"\u003e\u003ci class=\"icon\" data-lucide=\"file-check\"\u003e\u003c\/i\u003e Official COA\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"coa\" aria-labelledby=\"coa-h\"\u003e\n\u003ch2 id=\"coa-h\"\u003eVerified Purity: Official Certificate of Analysis\u003c\/h2\u003e\n\u003cp\u003eTransparency and trust are our top priorities. We utilize official third-party lab testing to ensure our standardized extracts meet the highest quality and safety standards. Our Dioscorea extract is officially verified for its high active concentration.\u003c\/p\u003e\n\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0769\/4362\/2362\/files\/Dioscorea_Standardized_Extract_CoA_diosgenin.pdf?v=1777339084\" target=\"_blank\" class=\"pill brand\" style=\"margin-top: 10px;\"\u003e\u003ci class=\"icon\" data-lucide=\"file-text\"\u003e\u003c\/i\u003e View Official Lab COA\u003c\/a\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"tech-h\"\u003e\n\u003ch2 id=\"tech-h\"\u003eThe SNEDDS Advantage\u003c\/h2\u003e\n\u003cp\u003eActive botanical compounds like Dioscin and Diosgenin are highly beneficial, but they are naturally lipophilic, meaning they have poor absorption on their own. We formulated this product using a \u003cstrong\u003eSelf-Nanoemulsifying Dietary Delivery System (SNEDDS)\u003c\/strong\u003e with specialized excipients to bypass this issue. SNEDDS literally increases the bioavailability and permeability of active botanical compounds. It helps bypass first-pass metabolism and leads to a good amount of the botanical compounds going straight to the bloodstream. It is formulated for enhanced dispersion, engineered for better delivery so your body can actually absorb the active botanical compounds efficiently.\u003c\/p\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"science\" aria-labelledby=\"muscle-h\"\u003e\n\u003ch2 id=\"muscle-h\"\u003eTraining Performance \u0026amp; Support\u003c\/h2\u003e\n\u003cp class=\"lead\" style=\"margin-bottom: 0.5rem;\"\u003eDiosgenin has a molecular structure remarkably similar to that of DHEA.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"activity\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eSupports Muscle Function.\u003c\/strong\u003e When combined with resistance training, standardized \u003cem\u003eDioscorea\u003c\/em\u003e has been researched for its ability to support exercise readiness and overall muscle quality.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"zap\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eAnabolic Ceiling.\u003c\/strong\u003e Diosgenin carries strong theoretical potential as a natural anabolic for muscle, it is a steroidal sapogenin with meaningful anabolic signaling properties. While Osstivia currently holds more published muscle data (Ursolic Acid, Oleanolic Acid, Salidroside), Diosgenin's overall ceiling for muscle support may be even higher.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"shield-check\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eStandardized Extract.\u003c\/strong\u003e Engineered for better delivery, this formulation provides a highly concentrated, standardized dose (\u0026gt;40% Diosgenin) to ensure consistent support without the drawbacks of synthetic harsh compounds.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"neuro-h\"\u003e\n\u003ch2 id=\"neuro-h\"\u003eNeuroprotection \u0026amp; Cognitive Performance\u003c\/h2\u003e\n\u003cp class=\"lead\" style=\"margin-bottom: 0.5rem;\"\u003eDiosgenin demonstrates remarkable neuroprotective potential, unlocking new possibilities for brain health when bioavailability is optimized.\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"brain\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eBrain Bioavailability.\u003c\/strong\u003e The historical issue with Diosgenin for brain diseases has been absorption. However, a recent paper demonstrated that utilizing a SNEDDS formulation drastically increased the brain bioavailability of Diosgenin in mouse models, showing immense promise for human use.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"lightbulb\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eCognitive Support.\u003c\/strong\u003e Beyond theoretical models, placebo-controlled human trials have shown that Dioscorea extracts provide meaningful improvements in cognitive performance, demonstrating strong potential for overall neuro-support.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"metabolic-h\"\u003e\n\u003ch2 id=\"metabolic-h\"\u003eMetabolic Conditioning\u003c\/h2\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"droplet\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eGlucose Metabolism.\u003c\/strong\u003e \u003cem\u003eDioscorea\u003c\/em\u003e has been studied for its role in upregulating GLUT-4 signaling and translocation, which supports healthy glucose metabolism and systemic balance.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"dosing\" aria-labelledby=\"dose-h\"\u003e\n\u003ch2 id=\"dose-h\"\u003eNew Measurement Dosing System\u003c\/h2\u003e\n\u003cp style=\"font-size: 0.95rem; color: var(--mut);\"\u003eWe have upgraded from drops to a precise measurement dropper (mL) for ease of use. \u003cstrong\u003eStart Low:\u003c\/strong\u003e We recommend starting at 0.5 mL and building up to the maximum dose of 2.0 mL daily.\u003c\/p\u003e\n\n\u003ch3\u003eHow long will your bottle last?\u003c\/h3\u003e\n\u003ctable class=\"dose-table\"\u003e\n\u003cthead\u003e\n\u003ctr\u003e\n\u003cth\u003eDaily Dose\u003c\/th\u003e\n\u003cth\u003e30mL Bottle\u003c\/th\u003e\n\u003cth\u003e60mL Bottle\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e0.5 mL\u003c\/strong\u003e (Low)\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003ctd\u003e4 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.0 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003ctd\u003e2 Months\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003e1.5 mL\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e20 Days\u003c\/td\u003e\n\u003ctd\u003e40 Days\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\n\u003cstrong\u003e2.0 mL\u003c\/strong\u003e (Max)\u003c\/td\u003e\n\u003ctd\u003e2 Weeks\u003c\/td\u003e\n\u003ctd\u003e1 Month\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp style=\"font-size: 0.85rem; color: var(--mut); margin-top: 10px;\"\u003e\u003cem\u003eNote: 10 drops is approximately 0.5 mL. Max recommended dose is 2mL\/day.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" aria-labelledby=\"ref-h\"\u003e\n\u003ch2 id=\"ref-h\"\u003eScientific References\u003c\/h2\u003e\n\u003cul style=\"padding-left: 20px; font-size: 0.85rem; color: var(--mut);\"\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eEffects of Dioscorea esculenta intake with resistance training on muscle hypertrophy and strength in sprint athletes.\u003c\/em\u003e Horii et al. (2020).\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eDioscorea esculenta-induced increase in muscle sex steroid hormones is associated with enhanced insulin sensitivity in a type 2 diabetes rat model.\u003c\/em\u003e Sato et al. FASEB Journal. (2017).\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eFormulation of a novel diosgenin-loaded nanoemulsion and its evaluation for improved brain bioavailability in the management of cerebral ischemia.\u003c\/em\u003e Ahmad et al. JDDST. (2025).\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eDiosgenin-Rich Yam Extract Enhances Cognitive Function: A Placebo-Controlled, Randomized, Double-Blind, Crossover Study of Healthy Adults.\u003c\/em\u003e Tohda et al. Nutrients. (2017).\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eChronic application and significant increase in 1RM leg press and 1RM bench press during strength training.\u003c\/em\u003e Poole et al. (2010).\u003c\/li\u003e\n\u003cli style=\"margin-bottom: 8px;\"\u003e\n\u003cem\u003eImprovements in endurance capacity in animal models and human interventions.\u003c\/em\u003e Ikeuchi et al. (2006); Goh et al. (2020); Herrick et al. (2020).\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.85rem; text-align: center;\"\u003e© Ossialabs — Advanced research-backed formulations.\u003cbr\u003eStatements have not been evaluated by the FDA. Not intended to diagnose, treat, cure, or prevent any disease.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n    \/* Reveal animation *\/\n    (function(){\n      try{\n        const io=new IntersectionObserver(es=\u003e{ es.forEach(e=\u003e{ if(e.isIntersecting){ e.target.classList.add('in'); io.unobserve(e.target);} }); },{threshold:.12});\n        document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eio.observe(el));\n      }catch(e){ document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eel.classList.add('in')); }\n    })();\n\n    \/* Parallax background *\/\n    (function(){\n      const root=document.getElementById('ossialabs-product');\n      let ticking=false, lastY=0;\n      function onScroll(){ lastY = window.scrollY || document.documentElement.scrollTop || 0; if(!ticking){ requestAnimationFrame(()=\u003e{ root.style.setProperty('--scrollY', String(lastY)); ticking=false;}); ticking=true; } }\n      window.addEventListener('scroll', onScroll, {passive:true}); 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transform:none }\n    }\n  \u003c\/style\u003e\n\u003cdiv id=\"ossialabs-product\" lang=\"en\" role=\"region\" aria-label=\"Product Details\"\u003e\n\u003cdiv class=\"fx-bg\" aria-hidden=\"true\"\u003e\u003cbr\u003e\u003c\/div\u003e\n\u003cdiv class=\"content\"\u003e\n\u003cdiv class=\"wrap\"\u003e\n\n\u003csection class=\"reveal\" aria-labelledby=\"hero-title\"\u003e\n\u003ch1 id=\"hero-title\"\u003eContributor Membership\u003c\/h1\u003e\n\u003cp class=\"lead\"\u003eBecome a foundational part of our exclusive membership. As a Contributor, you gain VIP access and incredible monthly perks while directly funding our future R\u0026amp;D, advanced SNEDDS engineering, and clinical research.\u003c\/p\u003e\n\u003cdiv style=\"margin-top: 12px;\"\u003e\n\u003ca class=\"pill brand\" href=\"#perks\"\u003e\u003ci class=\"icon\" data-lucide=\"award\"\u003e\u003c\/i\u003e View VIP Perks\u003c\/a\u003e\n\u003ca class=\"pill\" href=\"#mission\"\u003e\u003ci class=\"icon\" data-lucide=\"flask-conical\"\u003e\u003c\/i\u003e Fuel The Science\u003c\/a\u003e\n\u003c\/div\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"perks\" aria-labelledby=\"perks-h\"\u003e\n\u003ch2 id=\"perks-h\"\u003eExclusive Member Benefits\u003c\/h2\u003e\n\u003cp class=\"lead\" style=\"margin-bottom: 0.5rem;\"\u003eWe reward those who support the science. Every month, you receive:\u003c\/p\u003e\n\u003cul class=\"feature-list\"\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"gift\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003eMonthly Free Formula.\u003c\/strong\u003e Claim ONE free 30mL or 2oz supplement or skincare product of your choice, every single month.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"rocket\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePriority Fulfillment.\u003c\/strong\u003e Your orders shouldn't wait. Contributor orders automatically bypass the queue. They are picked, packed, and shipped out before non-membership customers.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"percent\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003e20% Sitewide Discount.\u003c\/strong\u003e Stack your formulation protocol for less. Enjoy an automatic, flat 20% off all your additional Ossialabs purchases every month.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003ci data-lucide=\"lightbulb\"\u003e\u003c\/i\u003e\n\u003cdiv\u003e\n\u003cstrong\u003ePriority R\u0026amp;D Influence.\u003c\/strong\u003e We listen to our members. Have a recommendation for a new research project or a new botanical product? Pitch it to us. If we love your idea, we will put it at the very top of our priority list for development.\u003c\/div\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/section\u003e\n\n\u003csection class=\"card reveal\" id=\"mission\" aria-labelledby=\"mission-h\"\u003e\n\u003ch2 id=\"mission-h\"\u003eMore Than A Subscription\u003c\/h2\u003e\n\u003cp\u003eOssialabs isn't a standard supplement and skincare company. We are an active research collective dedicated to advancing the science of bioavailability and human performance. By becoming a VIP Contributor, your membership directly funds the sourcing of rare botanicals, the engineering of new Self-Nanoemulsifying Dietary Delivery Systems (SNEDDS), and the execution of our future community-driven human trials.\u003c\/p\u003e\n\u003c\/section\u003e\n\n\u003cp class=\"lead\" style=\"margin-top: 20px; color: var(--mut); font-size: 0.85rem; text-align: center;\"\u003e© Ossialabs — Advancing the science, together.\u003cbr\u003eManage, pause, or cancel your membership at any time.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cscript\u003e\n    \/* Reveal animation *\/\n    (function(){\n      try{\n        const io=new IntersectionObserver(es=\u003e{ es.forEach(e=\u003e{ if(e.isIntersecting){ e.target.classList.add('in'); io.unobserve(e.target);} }); },{threshold:.12});\n        document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eio.observe(el));\n      }catch(e){ document.querySelectorAll('#ossialabs-product .reveal').forEach(el=\u003eel.classList.add('in')); }\n    })();\n\n    \/* Parallax background *\/\n    (function(){\n      const root=document.getElementById('ossialabs-product');\n      let ticking=false, lastY=0;\n      function onScroll(){ lastY = window.scrollY || document.documentElement.scrollTop || 0; if(!ticking){ requestAnimationFrame(()=\u003e{ root.style.setProperty('--scrollY', String(lastY)); ticking=false;}); ticking=true; } }\n      window.addEventListener('scroll', onScroll, {passive:true}); onScroll();\n      root.addEventListener('pointermove', e=\u003e{\n        const r=root.getBoundingClientRect(); const x=(e.clientX-r.left)\/r.width*100; const y=(e.clientY-r.top)\/r.height*100;\n        root.style.setProperty('--fx1', `${Math.max(10, Math.min(90, x + 8))}% ${Math.max(8, Math.min(92, y - 10))}%`);\n        root.style.setProperty('--fx2', `${Math.max(10, Math.min(90, x + 20))}% ${Math.max(8, Math.min(92, y + 8))}%`);\n        root.style.setProperty('--fx3', `${Math.max(10, Math.min(90, x - 30))}% ${Math.max(8, Math.min(92, y + 20))}%`);\n      }, {passive:true});\n    })();\n\n    \/* Icons *\/\n    (function(){ window.addEventListener('DOMContentLoaded',()=\u003e{ try{ lucide.createIcons(); }catch(e){} }); })();\n  \u003c\/script\u003e\n\u003c\/div\u003e","brand":"OssiaLabs","offers":[{"title":"Default Title","offer_id":47803386855642,"sku":null,"price":20.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0769\/4362\/2362\/files\/0dc7504f-6f93-4d23-a271-cd78605a2b3e.png?v=1777789999"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0769\/4362\/2362\/collections\/SNEDDS.png?v=1772065820","url":"https:\/\/ossialabs.com\/collections\/store-category.oembed","provider":"OssiaLabs","version":"1.0","type":"link"}