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Humulus Lupulus SNEDDS

Humulus Lupulus SNEDDS

Regular price $45.00 USD
Regular price $49.99 USD Sale price $45.00 USD
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This is a SNEDDS formulation of the Common Hops, Humulus Lupulus. Research on this herb has been emerging, with effects to sedative, anxiolytic, antidepressant, sleep-promoting, anti-inflammatory, anti-diabetic, antioxidant, antimicrobial, anticancer, phytoestrogenic, anti-obesity, anti-angiogenic, anti-biofilm, hepatoprotective, cardioprotective, neuroprotective, enzyme inhibitory (e.g., acetylcholinesterase, α-amylase, urease), gastrointestinal support, estrogenic modulation.

 

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Humulus lupulus SNEDDS — Advanced Phyto-Delivery
Self‑Nanoemulsifying Delivery (SNEDDS)

Humulus lupulus — Advanced Hop Extract

A modern SNEDDS formulation of Humulus lupulus (Common Hops) engineered for consistent dispersion and efficient uptake. Designed to highlight hops’ traditional calming profile while supporting broader antioxidant and wellness applications.

Botanical: Hop cones Standardized extract Solubilization-first design No artificial colors

Calming & Sleep‑Friendly

Hops have a long history of use for relaxation and sleep support. This formulation is designed to showcase that gentle, wind‑down profile without next‑day heaviness.

SNEDDS Technology

Self‑nanoemulsifying systems form fine droplets when mixed with GI fluids, helping fat‑soluble hop constituents disperse consistently across varied meal states.

Broad Botanical Spectrum

Delivers a standardized hop extract featuring known constituents (e.g., xanthohumol, humulone/lupulone, 8‑prenylnaringenin) alongside supportive terpenes and polyphenols.

Science Snapshot

Emerging research explores hops across several domains: sedative/anxiolytic and sleep‑promoting properties; antioxidant and anti‑inflammatory activity; metabolic and microbial pathways; enzyme interactions (e.g., acetylcholinesterase, α‑amylase, urease); and phytoestrogenic modulation. Evidence quality and human relevance vary by endpoint. Claims below are descriptive, not diagnostic or curative.

Delivery
Self‑nanoemulsifying (SNEDDS)
Dispersion
Fine droplet formation in aqueous GI conditions
Botanical
Humulus lupulus cone extract
Constituents
Xanthohumol, humulone, lupulone, 8‑prenylnaringenin (among others)
Solubilizers
Food‑grade oils/surfactants (SNEDDS system)
Intended Use
Dietary supplement / research formulation

Ingredient Architecture

Core Extract

  • Hops (Humulus lupulus) standardized cone extract
  • Constituent focus: prenylated flavonoids (e.g., xanthohumol), bitter acids (humulone/lupulone)
  • Botanical ID and quality confirmed via supplier CoA

SNEDDS System

  • Self‑emulsifies upon contact with GI fluids
  • Supports consistent dispersion independent of fed/fasted state
  • Built from food‑grade oil and surfactant components

How to Use

Suggested Protocol

  • Begin with the lowest effective serving in the evening.
  • Take with water; food is optional.
  • Allow 45–60 minutes to assess relaxation effects before bedtime.

Individual response varies. Do not combine with alcohol or sedatives.

Who It’s For

Adults seeking a calming botanical and modern delivery system. Not for children. See safety notes below regarding pregnancy, breastfeeding, hormone‑sensitive conditions, and medication interactions.

Quality & Transparency

Consistency

Batch‑to‑batch spec targets for identity and constituent profile. Each lot supported by supplier documentation.

Design Rationale

SNEDDS chosen to address the solubility and dispersion challenges of lipophilic hop constituents, supporting reliable GI presentation.

Formulation Integrity

Food‑grade excipients only; no artificial colors. Allergen statements available per batch.

Specifications (At‑a‑Glance)

ParameterOverview
FormatLiquid SNEDDS (bottle) or prefilled softgel (option‑dependent)
Botanical SourceHumulus lupulus cone extract (standardized)
AppearanceTransparent to lightly tinted oil; forms fine emulsion in water
Flavor/AromaMild hop/bitter notes
ExcipientsFood‑grade oil/surfactant blend suitable for SNEDDS
AllergensNo major allergens intentionally added (verify current lot)
StorageCool, dry place; protect from heat, light, and moisture

Safety & Responsible Use

Important: Hops may cause drowsiness. Avoid driving or operating machinery after use. Not recommended during pregnancy or breastfeeding. Individuals with hormone‑sensitive conditions or on medications (especially CNS depressants) should consult a qualified healthcare professional before use. Discontinue if adverse effects occur.

This product description reflects a formulation concept and does not diagnose, treat, cure, or prevent any disease. Statements have not been evaluated by the Food and Drug Administration.

What Sets It Apart

  • Modern delivery system for lipophilic phyto‑constituents
  • Standardized botanical with transparent quality positioning
  • Balanced, calming focus with broader antioxidant support
  • Minimalist excipient philosophy; food‑grade only

FAQ

What is SNEDDS?

SNEDDS stands for Self‑Nanoemulsifying Drug Delivery System. It is a blend of oil and surfactant components that spontaneously forms a fine emulsion in the gastrointestinal tract, helping disperse lipophilic compounds more consistently.

Will it make me sleepy?

Many people use hops in the evening for wind‑down and sleep support. Sensitivity varies; start low and assess personal response. Do not combine with alcohol or sedatives.

Is this estrogenic?

Hops contain prenylated flavonoids (e.g., 8‑prenylnaringenin) with phytoestrogenic activity. Effects depend on dose, metabolism, and context. Consult a clinician if you have hormone‑sensitive conditions.

Vegan or allergen‑free?

The base formulation uses plant‑derived excipients and contains no major allergens intentionally added. Always verify the current lot specification and softgel material (if applicable).

© Craniofacial Research Collective — Formulation concept for educational and product‑development use.